Test your lung cancer back Test your lung cancer back

LUNG CANCER

WILL TEST YOU.

TEST IT BACK.

Jason Day, PGA Champion

Mother, Dening, is living with lung cancer

“When my mum was diagnosed, if there was one thing I learned, it is how biomarker testing can help you understand your next steps.”

Learn more about their story here.

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A lung cancer diagnosis can test your strength. It can test your resilience. It can test the way you see your future. But someone with lung cancer can test it right back by testing for biomarkers.

Certain biomarkers can be the “drivers” that cause cancer to grow and spread. Testing for biomarkers can help you and your doctor decide the best treatments to stop the cancer from growing and spreading.

3 Steps to Testing It Back:

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Test for all common biomarkers that could be causing your cancer to grow and spread.

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Test results take time. By knowing all your biomarker test results, you can make the best treatment decision.

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Biomarker test results can tell your doctor what proven treatments are right for you and when to start them.

Learn about lung cancer Learn about lung cancer

Learning About Lung Cancer

Lung cancer is a complicated disease that involves many details beyond the first diagnosis. Lung cancer affects different people in different ways, so it’s important to learn about the type of cancer you have.

What you'll learn from a lung cancer diagnosis:

Two main lung cancer types: non-small cell and small cell

General lung cancer type:

The two main types are non-small cell and small cell. Non-small cell lung cancer (also called NSCLC) is the most common type of lung cancer.

Stages of lung cancer

Stage of lung cancer:

The main stages of lung cancer are stage 1 to stage 4. These may be expressed in Roman or Arabic numerals. The stages are represented by a combination of numbers and letters. Each measures the extent of the cancer.

But keep in mind, learning about cancer’s biomarkers is an important next step after an initial diagnosis.

Putting Lung Cancer to the Test

You won’t learn about all of cancer’s biomarkers from an initial diagnosis. Having biomarker testing may give you and your doctor a more complete picture of what could cause lung cancer to grow and spread.

Biomarker testing goes by many names. You may hear it referred to as:

MUTATION TESTING
GENETIC TESTING
MOLECULAR TESTING
GENOMIC TESTING

Two Ways to Test for Biomarkers:

Biopsy test for biomarkers
Blood test for biomarkers

People diagnosed with advanced or metastatic NSCLC usually test positive for at least one of these biomarkers:

  • ALK
  • BRAF
  • EGFR
  • NTRK
  • PD-L1
  • ROS1

Knowing your cancer has a specific biomarker means you can target that biomarker.

Finding the Right Treatment Options

It can take time to get biomarker testing results. Some will come back sooner than others. Getting your results will give your doctor more information to help ensure that you start on the right treatment option.

EGFR biomarker

One common biomarker that doctors look for is EGFR (also known as epidermal growth factor receptor).

If an EGFR biomarker is discovered, it can be treated with the right treatment option—which is why it’s so important to test for it.

peopl1

Up to

1 in 4

peopl2

people

with NSCLC have cancer that tests positive for the EGFR biomarker.1,2*

*These cases were specific to adenocarcinoma, a common type of NSCLC.

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Biomarker testing results may give your healthcare team all the information they need to make an informed treatment decision.

Dr. Michael Pritchett, DO
Pulmonologist, FirstHealth Moore Regional Hospital

1. Li T, Kung HJ, Mack PC, Gandara DR. Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. J Clin Oncol. 2013;31(8):1039-1049.

2. Sholl LM, Aisner DL, Varella-Garcia M, et al. Multi-institutional oncogenic driver mutation analysis in lung adenocarcinoma: the Lung Cancer Mutation Consortium experience. J Thorac Oncol. 2015;10(5):768-777.

Targeting EGFR+ Lung Cancer

If your lung cancer tests positive for an EGFR biomarker, you and your doctor may discuss targeted therapies. EGFR TKIs, a type of targeted therapy, attack EGFR mutations that drive certain types of lung cancer to grow and spread. As a result, targeted therapies can give you more time without cancer growing or spreading.

Targeted lung cancer therapy

EGFR TKIs are a form of targeted therapy. It is a once-daily pill. Targeted therapy is not chemotherapy or immunotherapy.

If you’ve already started on another treatment and later find out the lung cancer you have is EGFR+, targeted therapies may still be a treatment option for you. Talk with your doctor today to see if targeted therapy may be the right way to fight the type of lung cancer you have.

Talking with your doctor can help you find the right treatment. Start the discussion today.

Targeted therapies may help stop the growth and spread of certain cancers. Learn more here.

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Knowing your biomarkers helps us target your cancer more accurately.

Dr. Michael Pritchett, DO
Pulmonologist, FirstHealth Moore Regional Hospital